amino acids fmoc  (Chem Impex International)

Journal: Toxics

Article Title: Hsa_circ_0001944 Regulates FXR/TLR4 Pathway and Ferroptosis to Alleviate Nickel Oxide Nanoparticles-Induced Collagen Formation in LX-2 Cells

doi: 10.3390/toxics13040265

Figure Lengend Snippet: The antibody information.

Article Snippet: GPX4 , #32506 , 1:1000 , Signalway Antibody.

Techniques:

Journal: Toxics

Article Title: Hsa_circ_0001944 Regulates FXR/TLR4 Pathway and Ferroptosis to Alleviate Nickel Oxide Nanoparticles-Induced Collagen Formation in LX-2 Cells

doi: 10.3390/toxics13040265

Figure Lengend Snippet: Nickel oxide nanoparticles (NiONPs) caused ferroptosis and inflammation-related indicators in LX-2 cells. ( A ) Cell content of GSH and ROS fluorescent probe test (×200, n = 3). ( B – D ) Intracellular iron ion content detection. ( E – K ) Protein expression levels of NCOA4, GPX4, NF-κB, p-NF-κB, IL-1β and TNF-α. * p < 0.05, compared to the control group.

Article Snippet: GPX4 , #32506 , 1:1000 , Signalway Antibody.

Techniques: Expressing, Control

Journal: Toxics

Article Title: Hsa_circ_0001944 Regulates FXR/TLR4 Pathway and Ferroptosis to Alleviate Nickel Oxide Nanoparticles-Induced Collagen Formation in LX-2 Cells

doi: 10.3390/toxics13040265

Figure Lengend Snippet: Activation of ferroptosis alleviated the excessive deposition of collagen in LX-2 cells treated with NiONPs. ( A ) GSH and ROS fluorescent probe test (×200, n = 3). ( B – D ) Intracellular iron ion content detection. ( E – H ) Protein expression levels of GPX4, MMP2 and COL1A1. ( I , J ) Cell cycle assay. ( K , L ) Scratch healing test (×100, n = 3). * p < 0.05, compared to the control group; # p < 0.05, compared with the 5 μg/mL NiONPs group.

Article Snippet: GPX4 , #32506 , 1:1000 , Signalway Antibody.

Techniques: Activation Assay, Expressing, Cell Cycle Assay, Control

Journal: Toxics

Article Title: Hsa_circ_0001944 Regulates FXR/TLR4 Pathway and Ferroptosis to Alleviate Nickel Oxide Nanoparticles-Induced Collagen Formation in LX-2 Cells

doi: 10.3390/toxics13040265

Figure Lengend Snippet: Inhibition of Toll-like receptor 4 (TLR4) signaling pathway increased the ferroptosis features in LX-2 cells. ( A ) GSH and ROS fluorescent probe test (×200, n = 3). ( B – D ) Intracellular iron ion content detection. ( E – H ) Protein expression levels of GPX4, NF-κB and IL-1β. * p < 0.05, compared to the control group; # p < 0.05, compared with the 5 μg/mL NiONPs group.

Article Snippet: GPX4 , #32506 , 1:1000 , Signalway Antibody.

Techniques: Inhibition, Expressing, Control

Journal: Toxics

Article Title: Hsa_circ_0001944 Regulates FXR/TLR4 Pathway and Ferroptosis to Alleviate Nickel Oxide Nanoparticles-Induced Collagen Formation in LX-2 Cells

doi: 10.3390/toxics13040265

Figure Lengend Snippet: Activation of Farnesol X receptor (FXR) signaling pathway increased the ferroptosis features in LX-2 cells. ( A ) GSH and ROS fluorescent probe test (×200, n = 3). ( B – D ) Intracellular iron ion content detection. ( E – H ) Protein expression levels of GPX4, NF-κB and IL-1β. * p < 0.05, compared to the control group; # p < 0.05, compared with the 5 μg/mL NiONPs group.

Article Snippet: GPX4 , #32506 , 1:1000 , Signalway Antibody.

Techniques: Activation Assay, Expressing, Control

Journal: Toxics

Article Title: Hsa_circ_0001944 Regulates FXR/TLR4 Pathway and Ferroptosis to Alleviate Nickel Oxide Nanoparticles-Induced Collagen Formation in LX-2 Cells

doi: 10.3390/toxics13040265

Figure Lengend Snippet: Overexpression of hsa_circ_0001944 alleviated the nickel oxide nanoparticles (NiONPs)-induced collagen in LX-2 cells through regulated Farnesol X receptor (FXR)/Toll-like receptor 4 (TLR4) signaling pathway and ferroptosis. ( A – G ) Protein expression levels of FXR (NR1H4), TLR4, GPX4, NF-κB, IL-1β and COL1A1. ( H – J ) Intracellular iron ion content detection. * p < 0.05, compared to the control group; # p < 0.05, compared with the 5 μg/mL NiONPs group.

Article Snippet: GPX4 , #32506 , 1:1000 , Signalway Antibody.

Techniques: Over Expression, Expressing, Control